WebChs7 could also be required for Chs3 activity at the PM through an unknown mechanism [38]. ... yeast form C. albicans and C. albicans cultured in the same medium without vaginal epithelial cells ... WebJun 14, 1999 · The Saccharomyces cerevisiae CHS7 gene encodes an integral membrane protein located in the ER which is directly involved in chitin synthesis through the regulation of chitin synthase III (CSIII) activity. In the absence of CHS7 product, Chs3p, but not other secreted proteins, is retained in the ER, leading to a severe defect in CSIII activity and …
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