WebFeb 18, 2024 · Liver or kidney problems. Cymbalta isn’t recommended for people with severe liver or kidney problems, such as liver disease or kidney disease. Taking this drug may worsen these conditions. If ... WebJul 25, 2024 · Dosage for long-term muscle and bone pain. Cymbalta is used to treat chronic musculoskeletal pain in adults. “Chronic” means long term. And …
Cymbalta and Renal failure acute, a phase IV clinical ...
WebCymbalta (duloxetine) Cymbalta (duloxetine) is in the drug class SSRI. Cymbalta is prescribed for the treatment of depression, generalized anxiety disorder, and neuropathic pain associated with diabetic peripheral neuropathy. The most common side effects of Cymbalta are nausea, dry mouth, constipation, diarrhea, insomnia, and dizziness. WebSep 6, 2024 · Cymbalta should be given without regard to meals.Initial TreatmentMajor Depressive Disorder -- Cymbalta should be administered at a total dose of 40 mg/day … normandy ave colchester
Cymbalta (Duloxetine) Serotonin and Norepinephrine Reuptake …
WebFeb 1, 2024 · Adults—At first, 60 milligrams (mg) once a day. Some patients may start at 30 mg once a day for 1 week before increasing the dose to 60 mg once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 120 mg per day. WebThe renally excreted metabolites 4-hydroxy duloxetine glucuronide and 5-hydroxy, 6-methoxy duloxetine sulphate were 7–9 times higher than in people with normal renal function; Contraindicated in uncontrolled hypertension due to potential risk of hypertensive crisis See how to identify renal failure stages according to GFR calculation WebRenal Insufficiency — Limited data are available on the effects of duloxetine in patients with end-stage renal disease (ESRD). After a single 60-mg dose of duloxetine, Cmax and AUC values were approximately 100% greater in patients with end-stage renal disease receiving chronic intermittent hemodialysis than in subjects with normal renal ... normandy auto body