Growth factor independence 1
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Growth factor independence 1
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WebHigh-mobility group proteins are a superfamily of DNA-binding proteins that bind to the DNA minor groove and bend it, whereas most of the transcription factors such as centromere protein B (CENP-B), octamer (Oct)-1, growth factor independence 1 (Gfi-1), and WRKY bind to the major groove of DNA. WebJan 23, 2007 · The expression of the transcription factor growth factor independence-1 (Gfi-1), however, was found to be markedly reduced in our SGD patient despite the …
WebMar 1, 2024 · AbstractColorectal cancer is the third most common cancer and the third leading cause of cancer death in the United States. Growth factor–independent 1 … WebGrowth factor independence 1 (Gfi-1) has been widely studied for its anti-inflammatory and anti-apoptotic effects. However, whether Gfi-1 has similar effects on H9c2 cardiomyocytes has not yet been reported. In this study, we explored the effect of Gfi-1 on lipopolysaccharide (LPS)-induced inflammatory responses and apoptosis in H9c2 cells.
WebSummary. This review concentrates on growth autonomy of tumor cells in relation to tumor progression. Human malignant melanoma serves as an example for progressive growth … WebAug 7, 2003 · The growth factor independence of HCT116 cells was shown to be dependent on autocrine transforming growth factor (TGF)-α activity, yet the isoparental HCT116b subcompartment showed similar levels of TGF-α expression as HCT116 when cells were in exponential growth. When both cell lines were growth arrested by nutrient …
WebSep 4, 2024 · Following selection for an IL2-independent phenotype, they cloned a full-length cDNA of the gene, symbolized Gfi1 for 'growth factor independence-1.' They speculated that the GFI1 protein may be involved in events occurring after the interaction of IL-2 with its receptor. Indeed, the GFI1 protein may regulate the expression of genes …
WebJul 28, 2024 · Although RUNX1T1 does not interact directly with DNA, it can be recruited by transcription factors, including growth factor independence-1 (GFI1), a critical erythroid transcription factor, and B-cell lymphoma-6 (BCL6), promyelocytic leukemia zinc finger protein (PLZF), and form multi-protein compound . iosh membership discount codeWebMay 2, 2016 · The transcriptional repressor growth factor independence 1 (GFI1) is comprised of conserved Snail/Slug/Gfi1 (SNAG) and zinc finger motifs separated by a linker region poorly conserved with GFI1B, its closest homolog. Moreover, GFI1 and GFI1B coordinate distinct developmental fates in hematopoiesis, suggesting that their functional … iosh member searchWebJan 1, 2009 · GFI1 (growth factor independence-1) is a zinc finger transcription factor controlling hematopoietic stem cell differentiation by controlling multiple target genes and regulatory microRNAs. on this day 26th novemberWebNov 16, 2008 · One of the transcription factor genes, which is aberrantly expressed in human T-cell lymphoma is Growth Factor Independence 1 (Gfi1). Since over … on this day 28th febWebGrowth factor independence 1 (GFI1) is an essential transcription factor expressed in the hair cells of mouse inner ear and Gfi1 locus serves as an excellent anchor site to drive the expression of inducible Cre recombinase in mouse inner hair cells. In this study, we have generated Gfi1-P2A-GFP-CreERT2 (Gfi1-GCE) knock-in mouse line by in-frame ... on this day 29th novemberWebThe growth factor independence-1 (Gfi1) transcription factor is required for proper development of neuroendocrine cells, sensory neurons, and blood. Patients with … on this day 28th marchWebThe DF acquires relative FSH-independence in order to continue growth and differentiation during further declining FSH concentrations. A transition from FSH- to LH-dependence is postulated as the mechanism for the continued development of the selected DF. ... In addition, FSH and insulin-like-growth factor (IGF) enhance each other's ability to ... onthisday 2/8