WebPhorbol 12-myristate 13-acetate (PMA) and ionomycin is used in vitro to activate T cells to proliferate and synthesize cytokines. PMA activates protein kinase C, while ionomycin is a calcium ionophore (a substance which can transport particular ions across a lipid membrane in a cell). Stimulation with PMA + ionomycin Webdescription Phorbol 12-myristate 13-acetate (PMA) is a diester of phorbol and activates the signal transduction enzyme protein kinase C (PKC). It is used as a tumor promoter and to …
PMA (Phorbol myristate acetate) NF-kB …
WebPhorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells. For research use only. We do not sell to patients. … WebCAS: 16561-29-8: Molecular Formula: C36H56O8: Molecular Weight (g/mol) 616.84: MDL Number: MFCD00036736: InChI Key: PHEDXBVPIONUQT-RGYGYFBISA-N: Synonym: … diabetes uk contact number
Phorbol myristate acetate: a mitogen sel…
WebPhorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a reversible, highly potent activator of protein kinase C (PKC), including Group A and Group B isoforms (Blumberg). PMA activates PKC isoforms through the binding of the C1 domain (Hurley et al.). PMA … WebDec 31, 1985 · Phorbol myristate acetate alone or in combination with calcium ionophore and cytokines has been shown to induce proliferation and activation, but little or no terminal differentiation of human... WebPhorbol-myristate acetate PMA (tumor promoter) tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a- (acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3- (hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa [3,4]benz [1,2-e]azulen-9 diabetes uk complications of diabetes