Webb1 juli 2013 · Because Smad4 is a central signaling molecule of TGF-β–induced signal transduction, we hypothesized that nestin expression status might depend on TGF-β1/Smad4 signaling. Nestin promoted tumor cell migration and induced EMT in PDAC We investigated whether nestin played a direct functional role in facilitating PDAC cell … WebbRecent breakthroughs in creating induced pluripotent stem cells (iPS cells) provide alternative means to obtain embryonic stem (ES) cell-like cells without destroying …
Anti Smad4 Antibody Santa Cruz Biotechnology Bioz
WebbTo establish the Smad4-expressing BxPC3 cells, we transfected 2μg pcDNA3 Flag-Smad4 vector to BxPC3 cells and selected as described previously. (2)The control cell line B3EV was established as described previously. (8) RNA interference. RNA interference against Smad4 has been described previously. WebbMissense SMAD4 mutations are prognostic determinants in patients with HNSCCs, ... In brief, 5-μm-thick tissue sections were dewaxed, rehydrated, and then incubated with monoclonal mouse anti-human SMAD4 antibody (sc-7966, 1:100 dilution; Santa Cruz Biotechnology, Santa Cruz, CA, USA) in a humidification chamber at 4°C overnight. northeastern charlotte campus
Anti-SMAD4 antibody (GTX112980) GeneTex
Webb10 feb. 2011 · Immunohistochemical staining was performed on 5-μm sections of the TMAs to assess cytoplasmic PTEN (PN37, rabbit polyclonal, 18-0256, Zymed), … WebbDownload scientific diagram Smad3 and Smad4 cooverexpression represses endogenous c- myc expression. (A) BALB/MK cells either were treated with 400 nM TGF-  or vehicle … Webb2 sep. 2024 · Smad4 serves as a tumor modulator by monitoring chemoresistance, angiogenesis, and vessel hyperpermeability. 15 - 17 Ozawa et al. 18 found that Smad4 … north eastern chow chow club